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Stay in Santa Cruz Region's best hotels!

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Wonderful: 9+ Very Good: 8+ Good: 7+ Pleasant: 6+
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Chairu Eco Hotel

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a concierge service and a tour desk. The staff is very helpful and kind, specialy Francisco he was very professional and helpful.

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9
Wonderful
843 reviews
Price from
$52.80
per night

TRYP by Wyndham Santa Cruz

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,... Beautiful brand new hotel. Huge rooms, great breakfast ( the lady making omelettes was lovely) nice pool. Spotless

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9
Wonderful
489 reviews
Price from
$67.15
per night

YVY CASA HOTEL

Hotel in Samaipata

Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace. This is simply a fantastic place to stay. The architecture is beautiful, and the rooms spacious, with comfortable beds. It is very quiet and relaxing. Breakfast was excellent and staff very friendly and helpful. The hotel is just a short walk away from the center of Samaipata. There’s a kitchen that you can use to cook.

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9.2
Wonderful
328 reviews
Price from
$37.62
per night

Marriott Santa Cruz de la Sierra Hotel

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness center, a shared lounge and terrace in Santa Cruz de la Sierra. the staff was exceptionally well trained, kindly and helpful

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9.1
Wonderful
336 reviews
Price from
$96
per night

Cosmopolitano Hotel Boutique

Hotel in Santa Cruz de la Sierra

Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical center of Santa Cruz de la Sierra. Guests can enjoy the on-site bar. Amazing hospitality from the staff here, especially Valeria who we interacted with most during our stay. She has been very helpful and friendly :)! We really liked what they did here with the rooms and common areas, very thoughtful design and we felt like we were in an oasis! We had stayed here for 2 nights and wouldn't mind it to be longer 👍🏻

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9.1
Wonderful
986 reviews
Price from
$88.76
per night

La Vida es Bella

Hotel in Samaipata

Located in Samaipata, 5.6 miles from Samaipata Fort, La Vida es Bella provides accommodations with a garden, free private parking, a shared lounge and a terrace. Beautiful place! Really quiet and relaxing and the staff was so helpful and kind. Can't recommend this place enough and we look forward to come back!

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9.3
Wonderful
117 reviews
Price from
$60
per night

El Pueblito Hotel Boutique

Hotel in Samaipata

Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge. Very charming property with super friendly staff

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9.5
Exceptional
230 reviews
Price from
$87
per night

Alfonsina Hotel Boutique

Hotel in Santa Cruz de la Sierra

Conveniently located only a 10-minute walk from Ventura Shopping Center, Alfonsina Hotel Boutique. offers accommodations in Santa Cruz de la Sierra. Very beautiful hotel in Santa Cruz. The room we had was spacious, very comfortable and clean - and nicely decorated with lots of cinema references.The breakfast was delicious too. The hotel is a bit off from the historic center but it is a short ride or a slightly longer walk. We would definitely come back and stay here again!

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9.4
Wonderful
408 reviews
Price from
$94.50
per night

Hotel Cortez

Hotel in Santa Cruz de la Sierra

Boasting an outdoor swimming pool, gym and spa facilities, Hotel Cortez has chic and spacious rooms in Santa Cruz de la Sierra. Free WiFi access is available. It is a corporate style hotel in a good location with good facilities, including a swimming pool. In walking distance of the main square.

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9
Wonderful
181 reviews
Price from
$112.50
per night

Rústico & Hotel Boutique Las Churapas

Hotel in San José de Chiquitos

Rústico & Hotel Boutique Las Churapas features an outdoor swimming pool, garden, a terrace and bar in San José de Chiquitos. The hotel provides both free WiFi and free private parking. This is the best hotel in Bolivia! An incredible nature retreat, swim in crystalline water with macaws flying overhead and the smell of blooming gardenia in the air. Run by the kindest people. Highly recommend!

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9.2
Wonderful
95 reviews
Price from
$38
per night

Hotels with extra health and safety measures

Find hotels in Santa Cruz Region with added hygiene measures plus high cleanliness ratings

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Most-booked hotels in Santa Cruz Region in the past month

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