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Comfort Inn Edwardsville - St. Louis is conveniently located off Interstate 270, just two miles from Southern Illinois University Edwardsville.

Conveniently located off Interstate 55 and Interstate 70, the Comfort Inn Collinsville near St Louis offers an ideal location to enjoy everything the St. Louis and the Metro-East areas have to offer.

Located off the Homer Adams Parkway in Alton, Illinois, this hotel is a 15-minute drive from the Lewis and Clark Historic Site. It features an indoor pool and free Wi-Fi.

The Quality Inn hotel is conveniently located off Interstate 64, minutes from Southwestern Illinois College Belleville Campus. This O'Fallon, IL hotel is just 14 miles from downtown St. Louis.

Offering convenient access to downtown St. Louis, the Sleep Inn O'Fallon near I-64 hotel in O’Fallon, Illinois is close to several shopping malls and industrial parks, including St. Clair Square Mall....